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Search Results for " cell proliferation. "

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ERK CDK

666

阻害剤

135

天然化合物

349

リコンビナントタンパク質

ライブラリー

TargetMolキット

カタログ番号	製品名	別名	ターゲット
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
T11960	MBM-55		GSK-3 , MAPK , DYRK , Akt , Chk , Bcr-Abl , CDK , S6 Kinase , Aurora Kinase

T9810	TNIK-IN-5		Wnt/beta-catenin
	TNIK-IN-5 is an potent TNIK inhibitor (IC50= 0.05 μM). TNIK-IN-5 potently inhibits Wnt signaling in intact cells. TNIK-IN-5 exhibits excellent in vitro anti-colorectal cancer activity.		Wnt/beta-catenin
T7200	TAK-960		PLK
	TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.		PLK
T2055	WS3		EGFR , IκB/IKK
	WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.		EGFR , IκB/IKK
T1923	BRD4770		Histone Methyltransferase
	BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.		Histone Methyltransferase
T4356	POL1-IN-1	Compound 3A	DNA/RNA Synthesis
	POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.		DNA/RNA Synthesis
T11438	GNE-1858		Others , MAPK
			Others , MAPK
T3209	AMG-337	AMG337	c-Met/HGFR
	AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).		c-Met/HGFR
T5414	Glumetinib	SCC244	c-Met/HGFR
	Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).		c-Met/HGFR
T20533	NNK	Nicotine-derived nitrosamine ketone	Lipoxygenase
	NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.		Lipoxygenase
T6941	PI-1840	PI 1840	PARP , Proteasome
	PI-1840（IC50 = 27 nM）is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).		PARP , Proteasome
T28036	MI-2-2	MI22,MI 2 2	Histone Methyltransferase
	MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.		Histone Methyltransferase
T9102	WM-3835		Apoptosis , Histone Methyltransferase , Histone Acetyltransferase
	WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.
T8756	KRAS inhibitor-9	DUN09716	Apoptosis , Ras
	KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ...		Apoptosis , Ras
T9195	SHR0302	ARQ252	Apoptosis , JAK
	SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).		Apoptosis , JAK
T8376	PKCβ inhibitor 1	KUN79359	Apoptosis , PKC
	PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively).		Apoptosis , PKC
T6351	MGCD-265 analog	MGCD-265,Glesatinib	Apoptosis , VEGFR , c-Met/HGFR
	MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.		Apoptosis , VEGFR , c-Met/HGFR
T2051	SKLB4771	FLT3-IN-1,FLT3-IN-1	FLT
	SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.		FLT
T8867	RO2959 Hydrochloride	RO2959 HCl	IL Receptor , Calcium Channel , Interleukin
	RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.		IL Receptor , Calcium Channel , Interleukin
T2514	Linifanib	ABT-869,RG3635,AL-39324	Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
	Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T11718	JI051	JI-051	Gamma-secretase
	JI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inh...		Gamma-secretase
T23119	Palmitoylisopropylamide		FAAH
	Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.		FAAH
T34280	Regrelor disodium	INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589	P2Y Receptor
	Regrelor disodium (INS 50589) is a p2y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, inhibits cell proliferation, and reduces inflammation.		P2Y Receptor
T24131	HDAC3-IN-T247	HDAC3 inhibitor T247,HDAC3 inhibitor-T247,HDAC3 IN T247,T247	Histone Demethylase , Antiviral
	HDAC3-IN-T247 (HDAC3 inhibitor T247) is a selective and potent histone deacetylase 3 (HDAC3) inhibitor with anticancer and antiviral activities.HDAC3-IN-T247 induces NF-κB acetylation in human colon cancer HCT116 cells i...		Histone Demethylase , Antiviral
T83643	4-Methylumbelliferyl heptanoate	4-Methylumbelliferyl enanthate
	4-Methylumbelliferyl heptanoate (4-Methylumbelliferyl enanthate) is a lipase fluorescent substrate that detects cell-mediated cytotoxicity and cell proliferation.
T72021	SU 5616	WAY-608241
	SU 5616 (WAY-608241) regulates abnormal cell proliferation and modulates tyrosine kinase signaling.
T9712	PF07104091	PF-07104091	CDK
	PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.		CDK
T10723	CDC25B-IN-1	ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate	Phosphatase
	CDC25B-IN-1 is an inhibitor of CDC25B with a Ki of 8.5 μM. CDC25B-IN-1 increases the G2/M phase by inhibiting cell proliferation and colony formation.		Phosphatase
T19826	Rabeprazole	LY307640	Potassium Channel , STAT
	Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis and can be used in the study of gastric ulcers.		Potassium Channel , STAT
T10784	CH6953755		Src
	CH6953755 is an orally active, potent and selective YES1 kinase inhibitor (IC50:1.8 nM).CH6953755 has anticancer activity and inhibits cancer cell proliferation by inhibiting YES1 kinase.		Src
T4235	Roblitinib	FGF-401	FGFR
	Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...		FGFR
T14902	CCT020312		PERK
	CCT020312 is a selective activator of EIF2AK3 and PERK. CCT020312 durably inhibits cell proliferation and elicits the phosphorylation of EIF2A.		PERK
T5322	BCI-121		Histone Methyltransferase
	BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.		Histone Methyltransferase
T6017	Linsitinib	OSI-906	IGF-1R
	OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...		IGF-1R
T23480	U-83836E		Others
	U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.		Others
T10276	AKT Kinase Inhibitor		Akt
			Akt
T83021	Antiproliferative agent-36		Others
	Antiproliferative agent-36 is a broad-spectrum anticancer benzothiazolylhydrazone-derived compound that inhibits cell proliferation.		Others
T12238	NNC 55-0396	NNC 55-0396 dihydrochloride	Calcium Channel
	NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation.		Calcium Channel
T2610L	BMS-599626 2HCL(714971-09-2 Free base)	BMS 599626 dihydrochloride,BMS-599626 2HCL(714971-09-2 Free base),AC480 2HCl	HER
	BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative. BMS-599626 is an orally available and selective dual inhibitor of HER1 and HER2 with IC50s of 20 and 30 nM, respectively. BMS-599626 inhibits tumor cell proliferat...		HER
T2110	(+)-JQ-1	JQ1	Epigenetic Reader Domain , Autophagy , Ligands for Target Protein for PROTAC
	(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility. (+)-JQ-1 induces cell autophagy and inhibits cell proliferation.
T5338	MTOR inhibitor-1		mTOR , Autophagy
	C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.		mTOR , Autophagy
T2060	ELR510444	LR-510444,LR510444,LR 510444	Apoptosis , Microtubule Associated
	ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpress...		Apoptosis , Microtubule Associated
T63643	BI-4142		HER
	BI-4142 is an orally active, potent and selective HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.		HER
T6909	NSC348884		Apoptosis , p53
	NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.		Apoptosis , p53
T11947	MARK4 inhibitor 1		Apoptosis , Others , AMPK
	MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.		Apoptosis , Others , AMPK
T2441	TAS-301	TAS 301	PKC
	TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.		PKC
T78212	RMC-9805	KRAS G12D inhibitor 18,KRAS G12D IN 18	Others
	RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.		Others
T35566	RBPJ Inhibitor-1	RIN1	Gamma-secretase
	RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell proliferation[1].		Gamma-secretase
T13000	Src Inhibitor 3		Others , Src
			Others , Src

Compounds

Target: GSK-3, MAPK, DYRK, Akt, Chk, Bcr-Abl, CDK, S6 Kinase, Aurora Kinase

TNIK-IN-5

T9810

Synonym:

Target: Wnt/beta-catenin

Target: EGFR, IκB/IKK

BRD4770

T1923

Synonym:

Target: Histone Methyltransferase

POL1-IN-1

T4356

Synonym: Compound 3A

Target: DNA/RNA Synthesis

Synonym: Nicotine-derived nitrosamine ketone

Target: PARP, Proteasome

MI-2-2

T28036

Synonym: MI22,MI 2 2

Target: Histone Methyltransferase

WM-3835

T9102

Synonym:

Target: Apoptosis, Histone Methyltransferase, Histone Acetyltransferase

KRAS inhibitor-9

T8756

Synonym: DUN09716

Target: Apoptosis, Ras

SHR0302

T9195

Synonym: ARQ252

Target: Apoptosis, JAK

PKCβ inhibitor 1

T8376

Synonym: KUN79359

Target: Apoptosis, PKC

MGCD-265 analog

T6351

Synonym: MGCD-265,Glesatinib

Target: Apoptosis, VEGFR, c-Met/HGFR

SKLB4771

T2051

Synonym: FLT3-IN-1,FLT3-IN-1

Target: IL Receptor, Calcium Channel, Interleukin

Linifanib

T2514

Synonym: ABT-869,RG3635,AL-39324

Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy

JI051

T11718

Synonym: JI-051

Target: Gamma-secretase

Palmitoylisopropylamide

Synonym: INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589

Target: P2Y Receptor

HDAC3-IN-T247

T24131

Synonym: HDAC3 inhibitor T247,HDAC3 inhibitor-T247,HDAC3 IN T247,T247

Target: Histone Demethylase, Antiviral

4-Methylumbelliferyl heptanoate

T83643

Synonym: 4-Methylumbelliferyl enanthate

Synonym: ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate

Target: Potassium Channel, STAT

Target: Histone Methyltransferase

Antiproliferative agent-36

Synonym: NNC 55-0396 dihydrochloride

Target: Calcium Channel

BMS-599626 2HCL(714971-09-2 Free base)

T2610L

Synonym: BMS 599626 dihydrochloride,BMS-599626 2HCL(714971-09-2 Free base),AC480 2HCl

Target: Epigenetic Reader Domain, Autophagy, Ligands for Target Protein for PROTAC

mTOR inhibitor-1

T5338

Synonym:

Target: mTOR, Autophagy

ELR510444

T2060

Synonym: LR-510444,LR510444,LR 510444

Target: Apoptosis, Microtubule Associated

Target: Apoptosis, p53

MARK4 inhibitor 1

T11947

Synonym:

Target: Apoptosis, Others, AMPK

Synonym: KRAS G12D inhibitor 18,KRAS G12D IN 18

Target: Gamma-secretase

カタログ番号	製品名	別名	ターゲット
TN1124	Neoeriocitrin		AChE
	Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor.		AChE
T2988	(-)-Epigallocatechin Gallate	Epigallocatechol Gallate,EGCG	Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
	(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
TN1237	3-O-Methylgallic acid	3,4-Dihydroxy-5-methoxybenzoic acid	Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
	3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation ...		Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
T22644	C2 Ceramide	Ceramide	Others
	A potent modulator of cell proliferation and differentiation.		Others
T3250	Royal Jelly acid	10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid	VEGFR , Endogenous Metabolite
	Royal Jelly acid (Queen Bee Acid) is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.		VEGFR , Endogenous Metabolite
T3S2325	Ardisiacrispin A	Saxifragifolin B,LTS-4,Deglucocyclamin	HSV
	Ardisiacrispin A (Deglucocyclamin) has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule...		HSV
TMA1122	N-Feruloylserotonin	(E/Z)-Moschamine,Moschamine	Antioxidant
	N-Feruloylserotonin ((E/Z)-Moschamine) is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.		Antioxidant
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
TN1600	Eclalbasaponin I		Others
	Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w...		Others
TN2304	Vitexin 2''-O-p-coumarate	Vitexin2''-O-p-coumarate,Vitexin 2''-O-p-coumarate	Others
	Vitexin 2''-O-p-coumarate (Vitexin2''-O-p-coumarate) is found in fenugreek seeds and promotes 2BS cell proliferation induced by H2O2.		Others
T14304	Aphidicolin		Others
	Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets D...		Others
T5S1882	Songorine	Napellonine,Zongorine,Bullatine G	Others , GABA Receptor
	Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.		Others , GABA Receptor
TN2058	Persicogenin		Anti-infection
	Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner.		Anti-infection
TQ0214	Dimethylcurcumin	ASC-J9,GO-Y025	Androgen Receptor
	Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion.		Androgen Receptor
T4085	Paris saponin VII	Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
TN2018	Orientin-2''-O-p-trans-coumarate		Others
	Orientin-2''-O-p-trans-coumarate is isolated from Trigonella foenum-graecum. Orientin-2''-O-p-trans-coumarate shows antioxidant activity and promotes cell proliferation.		Others
T3805	Prim-O-glucosylcimifugin	Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside	TNF , COX , JAK , NO Synthase
	Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.		TNF , COX , JAK , NO Synthase
TMA2474	δ-Tocotrienol	Delta-Tocotrienol	ERK , BCL , VEGFR , Akt , PI3K , PDK , p53
	δ-Tocotrienol (Delta-Tocotrienol) is a potential angiogenic inhibitor. δ-Tocotrienol is also a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSC-LC) cell proliferation, induce apoptosis...		ERK , BCL , VEGFR , Akt , PI3K , PDK , p53
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T36473	Trans-Nerolidol		Antifungal
	trans-Nerolidol is a sesquiterpene alcohol isolated from the above-ground parts of the Saharan Valerian plant with antifungal activity. trans-Nerolidol inhibits cell proliferation in a dose-dependent manner, and induces ...		Antifungal
TN1658	Ganoderenic acid D		Apoptosis , Others
	Ganoderenic acid D is a natural product isolated from the effective compounds of Ganoderma lucidum extract (GLE). Ganoderenic acid D induces cell cycle arrest and apoptosis and inhibits the proliferation of cancer cells.		Apoptosis , Others
TMS2182	Trans-Zeatinriboside	Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside	Others
	trans-Zeatinriboside (Ribosylzeatin) is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process,...		Others
T4928	L-Kynurenine	(S)-Kynurenine	AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
	L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...		AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
TN6739	Angoline	6-Methoxyldihydrochelerythrine	IL Receptor , STAT
	Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can...		IL Receptor , STAT
T2S1837	Steviol	NSC 226902,Hydroxydehydrostevic acid	Others
	1. Steviol (NSC-226902), a natural sweetener, it inhibits proliferation of the gastrointestinal cancer cells intensively. 2. Steviol can induce a significant increase in CYP3A29 expression. 3. Steviol inhibits the prolif...		Others
TN1805	Isosilybin B		Apoptosis , Androgen Receptor
	Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes to G1-phase blockade and apoptosis.Isosilybin B induces degr...		Apoptosis , Androgen Receptor
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
TN2190	Scoulerine		Apoptosis , Beta-Secretase , BACE , Parasite
	Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.		Apoptosis , Beta-Secretase , BACE , Parasite
T5780	HYPOCRELLIN B		Apoptosis , Parasite , Antifungal
	HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre...		Apoptosis , Parasite , Antifungal
TN1854	Lasiodin	Lasiokaurin	P450 , PARP , Caspase
	Lasiodin (Lasiokaurin) is a diterpene compound from the plant Camellia sinensis that inhibits the proliferation of NPC cells. Lasiodin has antioxidant, antitumor and antibacterial activities, induces cell cycle length an...		P450 , PARP , Caspase
TN1244	3'-Demethylnobiletin		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
	3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling ...		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
TN1346	Oxypalmatine	8-Oxypalmatine	Apoptosis
	Oxypalmatine (8-Oxypalmatine) is a berberine-type alkaloid isolated from Phellodendron amurense that regulates breast cancer cell proliferation and apoptosis by inhibiting PI3K/AKT signaling and its efficacy in breast ca...		Apoptosis
T5724	Neogambogic acid	neo-gambogic acid	Apoptosis , Others , Antibacterial
	Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of proliferation of human breast cancer cell li...		Apoptosis , Others , Antibacterial
T6742	2-Deoxy-D-glucose	2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,NSC 15193,2-DG	Apoptosis , Hexokinase , HSV
	2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis. 2-Deoxy-D-glucose has antiviral activity, as well as inhibitory cell proliferation and apoptosis-inducing activity.		Apoptosis , Hexokinase , HSV
T3900	Emodin-8-glucoside	Emodin glucoside B,Anthraglycoside B	Others
	Emodin-8-glucoside (Anthraglycoside B) functions to protect from focal cerebral injury induced by ischemia and reperfusion. Emodin-8-beta-D-glucoside directly stimulates cell proliferation and differentiation of osteobla...		Others
T4S1540	Myrislignan		Apoptosis , NF-κB
	Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc...		Apoptosis , NF-κB
T2220	2-Methoxyestradiol	NSC-659853,2-MeOE2,2-ME2	Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
	2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T21883	Gedunin		HSP
	Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.		HSP
T11363	Ganoderic acid F		Others
			Others
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
T14305	Apicidin	OSI 2040	Apoptosis , HDAC , Autophagy
	Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis ...		Apoptosis , HDAC , Autophagy
T2S0618	β-Elemonic Acid	3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid	Apoptosis , Reactive Oxygen Species , COX
	β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel...		Apoptosis , Reactive Oxygen Species , COX
T5S0527	Rhodojaponin III		Others
	1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin III and played a critical role. 2. Rhodoja...		Others
T3729	Ethyl gallate	Nipagallin A,Phyllemblin,gallic acid ethyl ester	MMP , NF-κB , Akt , Antibacterial
	Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhib...		MMP , NF-κB , Akt , Antibacterial
T3776	Rhapontigenin	Protigenin	P450 , Antibacterial , Antifungal
	Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. R...		P450 , Antibacterial , Antifungal
T5004	Hyaluronic acid sodium	Sodium Hyaluronate	Others
	Hyaluronic acid sodium (Sodium Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsu...		Others
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
TN6872	Trypsin		Protease-activated Receptor
	Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...		Protease-activated Receptor
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天然物製品

(-)-Epigallocatechin Gallate

T2988

Synonym: Epigallocatechol Gallate,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

3-O-Methylgallic acid

TN1237

Synonym: 3,4-Dihydroxy-5-methoxybenzoic acid

Target: Apoptosis, NF-κB, OCT, DNA/RNA Synthesis, STAT

Synonym: 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid

Target: VEGFR, Endogenous Metabolite

Ardisiacrispin A

T3S2325

Synonym: Saxifragifolin B,LTS-4,Deglucocyclamin

Target: HSV

N-Feruloylserotonin

TMA1122

Synonym: (E/Z)-Moschamine,Moschamine

Target: Antioxidant

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Vitexin 2''-O-p-coumarate

TN2304

Synonym: Vitexin2''-O-p-coumarate,Vitexin 2''-O-p-coumarate

Synonym: Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Persicogenin

TN2058

Synonym:

Target: Anti-infection

Dimethylcurcumin

TQ0214

Synonym: ASC-J9,GO-Y025

Target: Androgen Receptor

Paris saponin VII

T4085

Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Orientin-2''-O-p-trans-coumarate

TN2018

Synonym:

Target: Others

Prim-O-glucosylcimifugin

T3805

Synonym: Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside

Target: TNF, COX, JAK, NO Synthase

δ-Tocotrienol

TMA2474

Synonym: Delta-Tocotrienol

Target: ERK, BCL, VEGFR, Akt, PI3K, PDK, p53

Cinnamic acid

T5646

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Target: Apoptosis, Others

trans-Zeatinriboside

TMS2182

Synonym: Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside

Target: Others

L-Kynurenine

T4928

Synonym: (S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Angoline

TN6739

Synonym: 6-Methoxyldihydrochelerythrine

Target: IL Receptor, STAT

Steviol

T2S1837

Synonym: NSC 226902,Hydroxydehydrostevic acid

Target: Apoptosis, Androgen Receptor

Cnidicin

TN1516

Synonym:

Target: NOS, NO Synthase

Scoulerine

TN2190

Synonym:

Target: Apoptosis, Beta-Secretase, BACE, Parasite

HYPOCRELLIN B

T5780

Synonym:

Target: Apoptosis, Parasite, Antifungal

Lasiodin

TN1854

Synonym: Lasiokaurin

Target: P450, PARP, Caspase

3'-Demethylnobiletin

TN1244

Synonym:

Target: LDL, NF-κB, Integrin, Lipoxygenase, DNA/RNA Synthesis

Oxypalmatine

TN1346

Synonym: 8-Oxypalmatine

Target: Apoptosis

Neogambogic acid

T5724

Synonym: neo-gambogic acid

Target: Apoptosis, Others, Antibacterial

2-Deoxy-D-glucose

T6742

Synonym: 2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,NSC 15193,2-DG

Target: Apoptosis, Hexokinase, HSV

Emodin-8-glucoside

T3900

Synonym: Emodin glucoside B,Anthraglycoside B

Target: Apoptosis, NF-κB

2-Methoxyestradiol

T2220

Synonym: NSC-659853,2-MeOE2,2-ME2

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy

Hederacolchiside A1

T2P2806

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Target: Apoptosis, Others, NF-κB

Licochalcone B

T4S0350

Synonym:

Target: Beta Amyloid, Others

Apicidin

T14305

Synonym: OSI 2040

Target: Apoptosis, HDAC, Autophagy

β-Elemonic Acid

T2S0618

Synonym: 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid

Target: Apoptosis, Reactive Oxygen Species, COX

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester

Target: MMP, NF-κB, Akt, Antibacterial

Rhapontigenin

T3776

Synonym: Protigenin

Target: P450, Antibacterial, Antifungal

Hyaluronic acid sodium

T5004

Synonym: Sodium Hyaluronate

Target: Protease-activated Receptor

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01029	CAPN1 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His...
TMPJ-00761	FTH Protein, Human, Recombinant (His)	Human	E. coli
	Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is ta...
TMPJ-01404	TMX2 Protein, Human, Recombinant (His)	Human	E. coli
	TMX2 is a single-pass type I membrane protein and contains 1 thioredoxin domain. Thioredoxin plays an important role in various cellular processes through redox regulation. The Molecular Cloning and characterization of ...
TMPH-01299	EMC4 Protein, Human, Recombinant (His)	Human	E. coli
	Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates prot...
TMPJ-00724	LDHA Protein, Human, Recombinant (His)	Human	E. coli
	L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region,...
TMPH-02557	CAPN1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His...
TMPJ-00995	Serpin H1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is th...
TMPH-01036	Caprin-1/CAPRIN1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPJ-00038	IL-7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPJ-00059	IL-7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions...
TMPJ-00090	FGF-9 Protein, Human, Recombinant	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPJ-01470	SCF Protein, Human, Recombinant	Human	E. coli
	Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultu...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-03382	FGF-6 Protein, Human, Recombinant	Human	E. coli
	FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00831	Galectin-3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the ...
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293 Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPJ-00842	FGF-2 Protein, Rat, Recombinant	Rat	E. coli
	FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-00365	GALNT7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ...
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-00322	DEC-205 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPJ-00327	M-CSF/CSF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th...
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-00476	ITGB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPY-02483	ATP citrate lyase/ACLY Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP...
TMPY-01648	TREML2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPJ-01011	FGF-9 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine a...
TMPJ-01461	IL-15RA & IL-15 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N...
TMPJ-00037	FGF-2 Protein, Mouse, Recombinant	Mouse	E. coli
	FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPY-05176	AMH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ...
TMPJ-01462	IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f...
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPY-02259	FKBP25/FKBP3 Protein, Human, Recombinant (GST)	Human	E. coli
	FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation...
TMPH-01659	MAGEA4 Protein, Human, Recombinant (A173T, His & Myc)	Human	E. coli
	Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.
TMPJ-01196	ANGPTL8 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it a...
TMPH-02193	Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May be involved in cell proliferation and cell motility. Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.5 kDa and the accession number ...
TMPH-01658	MAGEA4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.
TMPH-02268	AGTR2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
TMPJ-01436	MKI67 Protein, Human, Recombinant (GST)	Human	E. coli
	MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferatio...
TMPK-01264	B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific ce...
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CAPN1 Protein, Human, Recombinant (His)

TMPH-01029

Species: Human

Expression System: E. coli

FTH Protein, Human, Recombinant (His)

TMPJ-00761

Species: Human

Expression System: E. coli

TMX2 Protein, Human, Recombinant (His)

TMPJ-01404

Species: Human

Expression System: E. coli

EMC4 Protein, Human, Recombinant (His)

TMPH-01299

Species: Human

Expression System: E. coli

LDHA Protein, Human, Recombinant (His)

TMPJ-00724

Species: Human

Expression System: E. coli

CAPN1 Protein, Mouse, Recombinant (His)

TMPH-02557

Species: Mouse

Expression System: E. coli

Serpin H1 Protein, Human, Recombinant (His)

TMPJ-00995

Species: Human

Expression System: HEK293 Cells

Caprin-1/CAPRIN1 Protein, Human, Recombinant (His)

TMPH-01036

Species: Human

Expression System: Baculovirus Insect Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: HEK293 Cells

IL-7 Protein, Mouse, Recombinant (His)

TMPJ-00038

Species: Mouse

Expression System: HEK293 Cells

PDGF-BB Protein, Mouse, Recombinant (His)

TMPJ-00562

Species: Mouse

Expression System: E. coli

IL-7 Protein, Human, Recombinant (His)

TMPJ-00059

Species: Human

Expression System: HEK293 Cells

FGF-9 Protein, Human, Recombinant

TMPJ-00090

Species: Human

Expression System: E. coli

SCF Protein, Human, Recombinant

TMPJ-01470

Species: Human

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

FGF-6 Protein, Human, Recombinant

TMPY-03382

Species: Human

Expression System: E. coli

IL-3 Protein, Mouse, Recombinant (His)

TMPJ-00051

Species: Mouse

Expression System: HEK293 Cells

Galectin-3 Protein, Mouse, Recombinant (His)

TMPK-00831

Species: Mouse

Expression System: HEK293 Cells

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00249

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

TMPJ-01467

Species: Human

Expression System: E. coli

FGF-2 Protein, Rat, Recombinant

TMPJ-00842

Species: Rat

Expression System: E. coli

TGF alpha Protein, Human, Recombinant

TMPY-03958

Species: Human

Expression System: E. coli

SCF Protein, Mouse, Recombinant

TMPJ-00166

Species: Mouse

Expression System: E. coli

GALNT7 Protein, Human, Recombinant (His)

TMPY-00365

Species: Human

Expression System: HEK293 Cells

TL1A/TNFSF15 Protein, Mouse, Recombinant

TMPJ-00603

Species: Mouse

Expression System: E. coli

DEC-205 Protein, Human, Recombinant (His)

TMPY-00322

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

TMPJ-01465

Species: Human

Expression System: E. coli

M-CSF/CSF1 Protein, Human, Recombinant (His)

TMPJ-00327

Species: Human

Expression System: HEK293 Cells

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TMPJ-01464

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (His)

TMPY-00476

Species: Human

Expression System: HEK293 Cells

APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TMPJ-00137

Species: Human

Expression System: HEK293 Cells

ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

TMPY-02483

Species: Human

Expression System: Baculovirus Insect Cells

TREML2 Protein, Human, Recombinant (His)

TMPY-01648

Species: Human

Expression System: HEK293 Cells

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

FGF-9 Protein, Mouse, Recombinant (His)

TMPJ-01011

Species: Mouse

Expression System: E. coli

IL-15RA & IL-15 Protein, Human, Recombinant (hFc)

TMPJ-01461

Species: Human

Expression System: HEK293 Cells

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

TMPY-02219

Species: H1N1

Expression System: E. coli

FGF-2 Protein, Mouse, Recombinant

TMPJ-00037

Species: Mouse

Expression System: E. coli

AMH Protein, Human, Recombinant (His)

TMPY-05176

Species: Human

Expression System: HEK293 Cells

IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)

TMPJ-01462

Species: Human

Expression System: HEK293 Cells

PADI4 Protein, Human, Recombinant (His)

TMPY-00021

Species: Human

Expression System: Baculovirus Insect Cells

FKBP25/FKBP3 Protein, Human, Recombinant (GST)

TMPY-02259

Species: Human

Expression System: E. coli

MAGEA4 Protein, Human, Recombinant (A173T, His & Myc)

TMPH-01659

Species: Human

Expression System: E. coli

ANGPTL8 Protein, Human, Recombinant (hFc)

TMPJ-01196

Species: Human

Expression System: HEK293 Cells

Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (His)

TMPH-02193

Species: Human

Expression System: P. pastoris (Yeast)

MAGEA4 Protein, Human, Recombinant (His)

TMPH-01658

Species: Human

Expression System: HEK293 Cells

AGTR2 Protein, Human, Recombinant (His & SUMO)

TMPH-02268

Species: Human

Expression System: E. coli

MKI67 Protein, Human, Recombinant (GST)

TMPJ-01436

Species: Human

Expression System: E. coli

B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)

TMPK-01264

Species: Cynomolgus

Expression System: HEK293 Cells

--------- More ---------

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L2151	Chemotherapy Drug Library	48 compounds
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L6100	Polyphenolic Natural Product Library	635 compounds
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L4000	Bioactive Compound Library	14439 compounds
	A collection of 14439 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;
L2200	Tyrosine Kinase Inhibitor Library	1016 compounds
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L1300	PI3K-AKT-mTOR Compound Library	420 compounds
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L2130	Anti-Cancer Metabolism Compound Library	1268 compounds
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L5300	Mitochondria-Targeted Compound Library	812 compounds
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